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Fabgennix
PKC eta Polyclonal Antibody
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Product Details
PKCETA-112AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 110-160 on human Protein Kinase C eta type protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC26269; MGC5363; nPKC-eta; PKC-L; Protein kinase C eta type; protein kinase C, eta; protein kinase C-eta
Gene Aliases: nPKC-eta; PKC-L; Pkch; PKCL; PRKCH; PRKCL
UniProt ID: (Human) P24723, (Mouse) P23298, (Rat) Q64617
Entrez Gene ID: (Human) 5583, (Mouse) 18755, (Rat) 81749
protein kinase C activity
calcium-independent protein kinase C activity
ATP binding
Ral GTPase binding
enzyme binding
metal ion binding
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
protein modifying enzyme
protein phosphorylation
signal transduction
positive regulation of macrophage derived foam cell differentiation
peptidyl-serine phosphorylation
platelet activation
negative regulation of glial cell apoptotic process
intracellular signal transduction
positive regulation of keratinocyte differentiation
positive regulation of B cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
positive regulation of glial cell proliferation
protein kinase C signaling
regulation of bicellular tight junction assembly
phosphorylation
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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