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Bethyl Laboratories
PKD2 Polyclonal Antibody
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Product Details
IHC-00570
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 825 and the C-terminus (residue 878).
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
PRKD2 (PKD2) is a member of the protein kinase D serine/threonine protein kinase family. PRKD2 is a component in the signal transduction pathway induced by phorbol esters and the CCK b gastrin receptor. It exhibits the strongest homology to the serine threonine protein kinases PKD/PKC and PKCnu, particularly in the duplex zinc finger-like cysteine-rich motif, in the pleckstrin homology domain and in the protein kinase domain. In contrast, it shows only a low degree of sequence similarity to other members of the PKC family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: nPKC-D2; PKD2; Serine/threonine-protein kinase D2; unnamed protein product
Gene Aliases: HSPC187; nPKC-D2; PKD2; PRKD2
UniProt ID: (Human) Q9BZL6
Entrez Gene ID: (Human) 25865
angiogenesis
positive regulation of endothelial cell proliferation
adaptive immune response
immune system process
protein phosphorylation
cell adhesion
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of endothelial cell migration
sphingolipid biosynthetic process
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of interleukin-2 production
positive regulation of interleukin-8 production
intracellular signal transduction
cellular response to vascular endothelial growth factor stimulus
positive regulation of blood vessel endothelial cell migration
positive regulation of fibroblast growth factor receptor signaling pathway
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
vascular endothelial growth factor receptor signaling pathway
T cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
endothelial tube morphogenesis
regulation of T cell apoptotic process
positive regulation of ERK1 and ERK2 cascade
positive regulation of DNA biosynthetic process
positive regulation of endothelial cell chemotaxis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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