This antibody is directed against the unphosphorylated form of PKD2, and the cross-reactivity with phosphorylated forms has not yet been determined.
Reconstitute in 100 µL of sterile water. When reconstituting, glycerol (1:1) may be added for an additional stability.
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A MGC138466; MGC138468; Polycystic kidney disease 2 protein homolog; polycystin 2; Polycystin-2; Transient receptor potential cation channel subfamily P member 2; TRPP1
Gene Aliases: C030034P18Rik; PC2; Pkd2; TRPP2
UniProt ID: (Mouse) O35245
Entrez Gene ID: (Mouse) 18764