This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: APKD2; Autosomal dominant polycystic kidney disease type II protein; MGC138466; MGC138468; PC2; PKD2; PKD4; polycystic kidney disease 2 (autosomal dominant); Polycystic kidney disease 2 protein; polycystin 2; Polycystin-2; Polycystwin; R48321; Transient receptor potential cation channel subfamily P member 2; transient receptor potential cation channel, subfamily P, member 2
Gene Aliases: APKD2; Pc-2; PC2; PKD2; PKD4; TRPP2
UniProt ID: (Human) Q13563
Entrez Gene ID: (Human) 5311