This target displays homology in the following species: Cow: 90%; Dog: 90%; Goat: 85%; Guinea Pig: 92%; Horse: 90%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
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Protein Aliases: cAMP-dependent protein kinase (catalytic subunit binding) inhibtor 2; cAMP-dependent protein kinase inhibitor beta; cAMP-dependent protein kinase inhibitor, testis isoform; PKI-beta; protein kinase (cAMP dependent, catalytic) inhibitor beta; protein kinase inhibitor beta, (cAMP-dependent, catalytic) inhibitor beta; protein kinase inhibitor beta, cAMP dependent, catalytic; protein kinase inhibitor beta, cAMP dependent, testis specific; protein kinase inhibitor, beta
Gene Aliases: PKINH; Prkacn2; RATPKINH
Entrez Gene ID: (Rat) 24678
Molecular Function: kinase inhibitor