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Invitrogen
PKMYT1 Polyclonal Antibody
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Product Details
PA5-17665
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Xenopus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues near the middle of mouse and human Myt1
Conjugate
Form
Liquid
Concentration
30 µg/mL
Amount
3 µg
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase; MYT1 kinase; protein phosphatase 1, regulatory subunit 126; unnamed protein product
Gene Aliases: 6230424P17; AW209059; MYT1; PKMYT1; PPP1R126; RGD1305434; XELAEV_18047881mg
UniProt ID: (Human) Q99640, (Mouse) Q9ESG9, (Xenopus) Q91618
Entrez Gene ID: (Human) 9088, (Mouse) 268930, (Rat) 287101, (Xenopus) 379626
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
metal ion binding
protein serine kinase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
regulation of cyclin-dependent protein serine/threonine kinase activity
G2/M transition of mitotic cell cycle
mitotic cell cycle
regulation of mitotic nuclear division
negative regulation of G2/M transition of mitotic cell cycle
meiotic cell cycle
negative regulation of G2/MI transition of meiotic cell cycle
protein phosphorylation
cell cycle
negative regulation of phosphatase activity
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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