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Invitrogen
PLA2G2A Polyclonal Antibody
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FIGURE: 1 / 3
PLA2G2A Antibody (PA5-47672) in IHC (F)
Immunohistochemical analysis of PLA2G2A in perfusion fixed frozen sections of mouse intestine. Samples were incubated in PLA2G2A polyclonal antibody (Product # PA5-47672) using a dilution of 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the cytoplasm of epithelial ... View More
Product Details
PA5-47672
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sf 21-derived recombinant mouse PLA2G2A Asn22-Cys146
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.1.1.4; EF; Enhancing factor; GIIC sPLA2; Group IIA phospholipase A2; modifier of Min1; non-pancreatic secreted type II phospholipase A2; Phosphatidylcholine 2-acylhydrolase 2A; Phospholipase A2, membrane associated; PLA2BPLA2; PLA2LPLA2S; secretory group II phospholipase A2
Gene Aliases: EF; Mom1; Pla2; Pla2g2a; sPLA2; sPla2-IIA
UniProt ID: (Mouse) P31482
Entrez Gene ID: (Mouse) 18780
lipid metabolic process
phospholipid metabolic process
negative regulation of cell proliferation
lipid catabolic process
somatic stem cell population maintenance
regulation of growth
regulation of cell proliferation
negative regulation of T cell proliferation
regulation of epithelial cell proliferation
negative regulation of epithelial cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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