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Abnova
PLA2G3 Polyclonal Antibody, MaxPab™
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Product Details
H00050487-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLA2G3 (AAH25316.1, 1 a.a. approximately 509 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGVQAGLFGM LGFLGVALGG SPALRWYRTS CHLTKAVPGN PLGYLSFLAK DAQGLALIHA RWDAHRRLQA CSWEDEPELT AAYGALCAHE TAWGSFIHTP GPELQRALAT LQSQWEACRA LEESPAGARK KRAAGQSGVP GGGHQREKRG WTMPGTLWCG VGDSAGNSSE LGVFQGPDLC CREHDRCPQN ISPLQYNYGI RNYRFHTISH CDCDTRFQQC LQNQHDSISD IVGVAFFNVL EIPCFVLEEQ EACVAWYWWG GCRMYGTVPL ARLQPRTFYN ASWSSRATSP TPSSRSPAPP KPRQKQHLRK GPPHQKGSKR PSKANTTALQ DPMVSPRLDV APTGLQGPQG GLKPQGARWV CRSFRRHLDQ CEHQIGPREI EFQLLNSAQE PLFHCNCTRR LARFLRLHSP PEVTNMLWEL LGTTCFKLAP PLDCVEGKNC SRDPRAIRVS ARHLRRLQQR RHQLQDKGTD ERQPWPSEPL RGPMSFYNQC LQLTQAARRP DRQQKSWSQ
Target Information
PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2; EC 3.1.1.4) proteins. These Ca(2+)-dependent lipolytic enzymes have a conserved Ca(2+)-binding loop and a his-asp dyad in the catalytic site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: giii; GIII sPLA2; Group 3 secretory phospholipase A2; group III secreted phospholipase A2; Group III secretory phospholipase A2; Phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII
Gene Aliases: GIII-SPLA2; PLA2G3; sPLA2-III; SPLA2III
UniProt ID: (Human) Q9NZ20, (Mouse) Q8BZT7
Entrez Gene ID: (Human) 50487, (Mouse) 237625
acrosome assembly
sperm axoneme assembly
lipoxygenase pathway
mast cell degranulation
phosphatidylcholine metabolic process
cell development
cilium morphogenesis
production of molecular mediator involved in inflammatory response
lipid metabolic process
phospholipid metabolic process
phosphatidylserine metabolic process
negative regulation of gene expression
positive regulation of macrophage derived foam cell differentiation
positive regulation of neuron projection development
cell projection organization
positive regulation of prostaglandin biosynthetic process
positive regulation of prostaglandin secretion
low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
macrophage activation
negative regulation of neuron apoptotic process
positive regulation of cell differentiation
phosphatidylethanolamine metabolic process
phosphatidylglycerol metabolic process
phosphatidic acid metabolic process
phosphatidylinositol metabolic process
cell maturation
arachidonic acid secretion
positive regulation of mast cell differentiation
positive regulation of cytokine production involved in inflammatory response
negative regulation of beta-amyloid clearance
positive regulation of histamine secretion by mast cell
regulation of endocytic recycling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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