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AbboMax
PLAC1 Polyclonal Antibody
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Product Details
602-980
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the C-terminus of mouse PLAC1 protein (from 145aa-175aa)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Human placenta tissue lysate.
Cellular location: Membrane, Secreted,.
Target Information
PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cancer/testis antigen 92; ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 26; EPCS26; PLAC1; plac1 {ECO:0000312|EMBL:AAH97979.1}; placenta-specific 1; Placenta-specific protein 1
Gene Aliases: CT92; DXWsu72e; Epcs26; OOSP2L; PLAC1
UniProt ID: (Human) Q9HBJ0, (Mouse) Q9JI83, (Rat) Q4V7E2
Entrez Gene ID: (Human) 10761, (Mouse) 56096, (Rat) 317316
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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