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Invitrogen
PLCB2 Polyclonal Antibody
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FIGURE: 1 / 6
PLCB2 Antibody (PA5-102006) in ICC/IF
Immunofluorescence analysis of PLCB2 was performed using 70% confluent log phase THP-1 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with PLCB2 Polyclonal Antibody (Product # PA5-102006) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790... View More
Product Details
PA5-102006
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PLCB2(Accession Q00722), corresponding to amino acid residues S341-I391.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PLCB2.
Target Information
PLCB2 is the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; Phosphoinositide phospholipase C-beta-2; phospholipase C, beta 2; Phospholipase C-beta-2; PKC beta II; PLC beta-2; PLC-beta-2; PLC-beta2; plcb2 {ECO:0000250|UniProtKB:Q00722}; PLCbeta-2; PLCbeta2
Gene Aliases: AI550384; B230205M18Rik; B230399N12; PLC-beta-2; PLCB2
UniProt ID: (Human) Q00722, (Rat) O89040, (Mouse) A3KGF7
Entrez Gene ID: (Human) 5330, (Rat) 85240, (Mouse) 18796
phospholipid metabolic process
activation of phospholipase C activity
Wnt signaling pathway, calcium modulating pathway
lipid catabolic process
intracellular signal transduction
inositol phosphate metabolic process
sensory perception of bitter taste
detection of chemical stimulus involved in sensory perception of bitter taste
metabolic process
phospholipid catabolic process
lipid metabolic process
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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