Search
Invitrogen
PLCB2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 2
PLCB2 Antibody (PA5-110178) in WB
Western blot analysis of PLCB2 in extracts of HEL cells. Samples were incubated with PLCB2 Polyclonal antibody (Product # PA5-110178) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-110178
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human PLCB2 (NP_0045642)
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Amount
150 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MSLLNPVLLP PKVKAYLSQG ERFIKWDDET TVASPVILRV DPKGYYLYWT YQSKEMEFLD ITSIRDTRFG KFAKMPKSQK LRDVFNMDFP DNSFLLKTLT VVSGPDMVDL TFHNFVSYKE NVGKAWAEDV LALVKHPLTA NASRSTFLDK ILVKLKMQLN SEGKIPVKNF FQMFPADRKR VEAALSACHL PKGKNDAIN
Target Information
PLCB2 is the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PKC beta II; PLC beta-2; PLC-beta-2; PLC-beta2; plcb2 {ECO:0000250|UniProtKB:Q00722}; PLCbeta-2; PLCbeta2; unnamed protein product
Gene Aliases: AI550384; B230205M18Rik; B230399N12; PLC-beta-2; PLCB2
UniProt ID: (Human) Q00722, (Rat) O89040, (Mouse) A3KGF7
Entrez Gene ID: (Human) 5330, (Rat) 85240, (Mouse) 18796
phosphatidylinositol phospholipase C activity
phospholipase C activity
calcium ion binding
protein binding
phospholipid binding
phosphoric diester hydrolase activity
hydrolase activity
G-protein beta/gamma-subunit complex binding
metal ion binding
phosphatidylinositol phospholipase C activity
signal transducer activity
phospholipase
detection of chemical stimulus involved in sensory perception of bitter taste
lipid metabolic process
phospholipid metabolic process
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
lipid catabolic process
intracellular signal transduction
phosphatidylinositol metabolic process
phosphatidylinositol-mediated signaling
sensory perception of bitter taste
release of sequestered calcium ion into cytosol
metabolic process
phospholipid catabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support