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Proteintech
PLD1 Polyclonal Antibody
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Product Details
18355-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLD1 fusion protein Ag13227
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: TTAHELRYQV PGSVHANVQL LRSAADWSAG IKYHEESIHA AYVHVIENSR HYIYIENQFF ISCADDKVVF NKIGDAIAQR ILKAHRENQK YRVYVVIPLL PGFEGDISTG GGNALQAIMH FNYRTMCRGE NSILGQLKAE LGNQWINYIS FCGLRTHAEL EGNLVTELIY VHSKLLIADD NTVIIGSANI NDRSMLGKRD SEMAVIVQDT ETVPSVMDGK EYQAGRFARG LRLQCFRVVL GYLDDPSEDI QDPVSDKFFK EVWVSTAARN ATIYDKVFRC LPNDEVHNLI QLRDFINKPV LAKEDPIRAE EELKKIRGFL VQFPFYFLSE ESLLPSVGTK EAIVPMEVWT
Target Information
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Choline phosphatase 1; hPLD1; mPLD1; phophatidylcholine-specific; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1
Gene Aliases: AA536939; C85393; PLD1; Pld1a; Pld1b
UniProt ID: (Human) Q13393
Entrez Gene ID: (Human) 5337, (Mouse) 18805
phosphatidic acid biosynthetic process
chemotaxis
small GTPase mediated signal transduction
Ras protein signal transduction
lipid catabolic process
regulation of microvillus assembly
inositol lipid-mediated signaling
cell motility
lipid metabolic process
phospholipid biosynthetic process
phospholipid catabolic process
regulation of cell migration
positive regulation of cell migration
response to peptide hormone
regulation of phagocytosis
defense response to Gram-positive bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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