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Proteintech
PLDN Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
10891-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLDN Fusion Protein Ag1337 (1-172 aa encoded by BC004819)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.15 mg/mL
Amount
22.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSVPGPSSP DGALTRPPYC LEAGEPTPGL SDTSPDEGLI EDLTIEDKAV EQLAEGLLSH YLPDLQRSKQ ALQELTQNQV VLLDTLEQEI SKFKECHSML DINALFAEAK HYHAKLVNIR KEMLMLHEKT SKLKKRALKL QQKRQKEELE REQQREKEFE REKQLTARPA KRM (1-172 aa encoded by BC004819)
Target Information
The aquaporins are a family of water-selective membrane channels. This gene encodes a member of a subset of aquaporins called the aquaglyceroporins. This protein allows passage of a broad range of noncharged solutes and also stimulates urea transport and osmotic water permeability. This protein may also facilitate the uptake of glycerol in hepatic tissue. The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 5, pallidin; biogenesis of lysosomal organelles complex-1, subunit 6, pallidin; biogenesis of organelles complex-1, subunit 6, pallidin; BLOC-1 subunit 6; BLOC-1 subunit pallidin; pallid protein; pallid protein homolog; pallidin; pallidin homolog; syntaxin 13 binding protein 1; syntaxin 13-interacting protein pallid; unnamed protein product
Gene Aliases: BLOC-1; BLOS6; HPS9; PA; PALLID; PLDN; Stx13bp1
UniProt ID: (Human) Q9UL45, (Mouse) Q9R0C0, (Rat) Q4V8A6
Entrez Gene ID: (Human) 26258, (Mouse) 18457, (Rat) 317630
angiogenesis
kidney development
vasculature development
bradykinin biosynthetic process
respiratory system process
endothelium development
cellular amino acid metabolic process
aspartate metabolic process
glutamate metabolic process
glutamine metabolic process
protein targeting
lipid metabolic process
phospholipid metabolic process
vesicle fusion
inflammatory response
immune response
response to oxidative stress
cytoskeleton organization
endosome organization
blood coagulation
memory
anterograde axonal transport
protein secretion
response to xenobiotic stimulus
gene expression
response to activity
endosomal transport
dentate gyrus development
hypothalamus development
actin cytoskeleton organization
melanocyte differentiation
lung development
neuron projection development
melanosome localization
melanosome transport
melanosome organization
positive regulation of natural killer cell activation
secretion of lysosomal enzymes
nitric oxide homeostasis
multicellular organism growth
locomotory exploration behavior
endosome to melanosome transport
swimming behavior
vasodilation
circadian sleep/wake cycle
pigmentation
skin development
ATP metabolic process
adenosine metabolic process
intracellular transport
developmental pigmentation
eye pigmentation
lung alveolus development
anterograde synaptic vesicle transport
dendrite morphogenesis
otolith development
homeostasis of number of cells
positive regulation of pigment cell differentiation
actin filament bundle assembly
actin filament network formation
lipid homeostasis
platelet dense granule organization
cilium morphogenesis
membrane fusion
triglyceride homeostasis
cellular response to epidermal growth factor stimulus
protein transmembrane transport
protein localization to membrane
protein localization to plasma membrane
regulation of plasma lipoprotein particle levels
axo-dendritic protein transport
protein localization to ciliary membrane
response to acetylcholine
translation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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