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Antibody detects endogenous levels of total PLEKHG5.
Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GEF720; Guanine nucleotide exchange factor 720; Neuronal RhoA GEF protein; NFkB activating protein; novel PH domain-containing protein; PH domain-containing family G member 5; pleckstrin homology domain containing family G member 5; pleckstrin homology domain containing, family G (with RhoGef domain) member 5; Pleckstrin homology domain-containing family G member 5; RhoA-specific guanine exchange factor SYX1; RhoA-specific guanine exchange factor SYX2; synectin-binding guanine exchange factor; Synectin-binding RhoA exchange factor; SYX; Transcript highly enriched in cortex and hippocampus
Gene Aliases: BC023181; CMTRIC; DSMA4; GEF720; KIAA0720; PLEKHG5; Syx; Tech
UniProt ID: (Human) O94827, (Rat) Q6RFZ7, (Mouse) Q66T02
Entrez Gene ID: (Human) 57449, (Rat) 310999, (Mouse) 269608
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