28154-1-AP detects the isoforms of PLEKHH3 protein around 80-85 kDa in SDS-PAGE.
PLEKHH3, a gene related to endothelial tight junction, is associated with obstructive sleep apnea (OSA) and angiogenesis. It has been reported that the expression of PLEKHH3 protein was increased in the OSA patients. PLEKHH3 may play a key role in OSA and angiogenesis by specifically regulating the endothelial cells formation of tight junctions.
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Protein Aliases: FLJ21019; PH domain-containing family H member 3; pleckstrin homology domain containing, family H (with MyTH4 domain) member 3; Pleckstrin homology domain-containing family H member 3; PLEKHH3
Gene Aliases: BC020025; PLEKHH3