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Invitrogen
PLK2 Polyclonal Antibody
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FIGURE: 1 / 2
PLK2 Antibody (PA5-79831) in IHC (P)
Immunohistochemistry (Paraffin) analysis of PLK2 in paraffin-embedded section of human tonsil tissues using PLK2 Polyclonal Antibody (Product # PA5-79831). Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution ) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 1 µg/mL dilution over... View More
Product Details
PA5-79831
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human PLK2 recombinant protein (Position: A94-Q188).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human MCF-7 cell, human HepG2 cell, mouse heart tissue. IHC: human tonsil tissue .
Target Information
PLK2 is a serum inducible serine/threonine kinase that is a member of the polo family of serine/threonine kinases which have a role in normal cell division. The kinase may play a role in embryogenesis, wound healing, and neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: h PLK-2; hSNK; PLK-2; polo-like kinase 1; Polo-like kinase 2; serine/threonine kinase; Serine/threonine-protein kinase PLK2; Serine/threonine-protein kinase SNK; Serum-inducible kinase; SNK; unnamed protein product
Gene Aliases: hPlk2; hSNK; PLK2; SNK
UniProt ID: (Human) Q9NYY3, (Mouse) P53351, (Rat) Q9R012
Entrez Gene ID: (Human) 10769, (Mouse) 20620, (Rat) 83722
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
ATP-dependent protein binding
protein serine kinase activity
signal transducer activity
transferase activity, transferring phosphorus-containing groups
protein complex binding
non-receptor serine/threonine protein kinase
protein modifying enzyme
G1/S transition of mitotic cell cycle
mitotic cell cycle
negative regulation of inflammatory response to antigenic stimulus
protein phosphorylation
mitotic spindle organization
Ras protein signal transduction
memory
positive regulation of autophagy
regulation of cell cycle process
negative regulation of angiogenesis
DNA damage response, signal transduction by p53 class mediator
Rap protein signal transduction
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein catabolic process
regulation of centriole replication
regulation of synaptic plasticity
long-term synaptic potentiation
long term synaptic depression
negative regulation of apoptotic process in bone marrow
positive regulation of cell migration involved in sprouting angiogenesis
negative regulation of cellular senescence
mitotic cell cycle checkpoint
phosphorylation
positive regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of dendritic spine development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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