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Invitrogen
PLK3 Polyclonal Antibody
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Product Details
PA5-76428
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein of human PLK3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
PLK3 is a member of the polo family of serine/threonine kinases. PLK3 is involved in the regulation of M phase in the cell cycle. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytokine inducible kinase; Cytokine-inducible serine/threonine-protein kinase; FGF-inducible kinase; PLK-3; Polo-like kinase 3; Proliferation-related kinase; serine-threonine kinase; Serine/threonine-protein kinase PLK3
Gene Aliases: CNK; FNK; PLK-3; PLK3; PRK
UniProt ID: (Human) Q9H4B4, (Rat) Q9R011
Entrez Gene ID: (Human) 1263, (Rat) 58936, (Mouse) 12795
nucleotide binding
p53 binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
protein serine kinase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
protein modifying enzyme
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
response to reactive oxygen species
protein phosphorylation
apoptotic process
response to osmotic stress
cellular response to DNA damage stimulus
mitotic spindle organization
endomitotic cell cycle
response to radiation
positive regulation of autophagy
regulation of cell cycle process
regulation of cell communication
regulation of signaling
DNA damage response, signal transduction by p53 class mediator
cytoplasmic microtubule organization
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cytokinesis
negative regulation of apoptotic process
mitotic G1/S transition checkpoint
positive regulation of protein catabolic process
regulation of cell division
negative regulation of protein kinase B signaling
Golgi disassembly
positive regulation of intracellular protein transport
regulation of signal transduction by p53 class mediator
positive regulation of chaperone-mediated autophagy
protein kinase B signaling
regulation of synaptic plasticity
regulation of long-term neuronal synaptic plasticity
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
cell cycle
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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