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Invitrogen
PLK3 Polyclonal Antibody
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Product Details
PA5-76428
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein of human PLK3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
PLK3 is a member of the polo family of serine/threonine kinases. PLK3 is involved in the regulation of M phase in the cell cycle. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytokine inducible kinase; Cytokine-inducible serine/threonine-protein kinase; FGF-inducible kinase; PLK-3; Polo-like kinase 3; Proliferation-related kinase; serine-threonine kinase; Serine/threonine-protein kinase PLK3
Gene Aliases: CNK; FNK; PLK-3; PLK3; PRK
UniProt ID: (Human) Q9H4B4, (Rat) Q9R011
Entrez Gene ID: (Human) 1263, (Rat) 58936, (Mouse) 12795
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
response to reactive oxygen species
protein phosphorylation
apoptotic process
response to osmotic stress
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic cell cycle checkpoint
endomitotic cell cycle
response to radiation
cytoplasmic microtubule organization
regulation of cytokinesis
negative regulation of apoptotic process
protein kinase B signaling
mitotic G1/S transition checkpoint
regulation of cell division
Golgi disassembly
positive regulation of intracellular protein transport
regulation of signal transduction by p53 class mediator
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
regulation of synaptic plasticity
regulation of long-term neuronal synaptic plasticity
cell cycle
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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