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Invitrogen
PLM Polyclonal Antibody
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Product Details
PA5-79288
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human FXYD1 recombinant protein (Position: E21-R92).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Liver Tissue, Rat Cardiac Muscle Tissue, Mouse Cardiac Muscle Tissue, HEPG2 whole cell, HELA whole cell. IHC: mouse cardiac muscle tissue, rat cardiac muscle tissue, human prostatic cancer tissue.
Target Information
This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FXYD domain-containing ion transport regulator 1; Phospholemman; Sodium Potassium ATPase; Sodium/potassium-transporting ATPase subunit FXYD1
Gene Aliases: 0610012C17Rik; 1110006M24Rik; FXYD1; PLM; Pml
UniProt ID: (Human) O00168, (Mouse) Q9Z239, (Rat) O08589
Entrez Gene ID: (Human) 5348, (Mouse) 56188, (Rat) 58971
chloride transport
muscle contraction
regulation of heart contraction
ion transmembrane transport
regulation of cardiac muscle cell membrane potential
chloride transmembrane transport
positive regulation of sodium ion export from cell
regulation of cardiac conduction
regulation of sodium ion transmembrane transporter activity
transport
ion transport
positive regulation of organic acid transport
regulation of cytosolic calcium ion concentration
regulation of cardiac muscle cell contraction
positive regulation of inorganic anion transmembrane transport
brain development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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