Product References
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Nature communications
Wu SA,Shen C,Wei X,Zhang X,Wang S,Chen X,Torres M,Lu Y,Lin LL,Wang HH,Hunter AH,Fang D,Sun S,Ivanova MI,Lin Y,Qi L
Tue May 30 00:00:00 EDT 2023
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Nature communications
Wu SA,Shen C,Wei X,Zhang X,Wang S,Chen X,Torres M,Lu Y,Lin LL,Wang HH,Hunter AH,Fang D,Sun S,Ivanova MI,Lin Y,Qi L
Tue May 30 00:00:00 EDT 2023
Decrease of lysyl hydroxylase 2 activity causes abnormal collagen molecular phenotypes, defective mineralization and compromised mechanical properties of bone.
Bone
Saito T,Terajima M,Taga Y,Hayashi F,Oshima S,Kasamatsu A,Okubo Y,Ito C,Toshimori K,Sunohara M,Tanzawa H,Uzawa K,Yamauchi M
Sat Jan 01 00:00:00 EST 2022
Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes.
Scientific reports
Terajima M,Taga Y,Nakamura T,Guo HF,Kayashima Y,Maeda-Smithies N,Parag-Sharma K,Kim JS,Amelio AL,Mizuno K,Kurie JM,Yamauchi M
Mon Aug 22 00:00:00 EDT 2022
Cerebral small vessel disease caused by PLOD3 mutation: Expanding the phenotypic spectrum of lysyl hydroxylase-3 deficiency.
Pediatric investigation
Zhou J,Feng W,Zhuo X,Lu W,Wang J,Fang F,Wang X
Thu Sep 01 00:00:00 EDT 2022
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway.
Cell death discovery
Chen Y,Ye B,Wang C,Nie Y,Qin J,Shen Z
Thu Jul 14 00:00:00 EDT 2022
Involvement of LH3 and GLT25D1 for glucosyl-galactosyl-hydroxylation on non-collagen-like domain of FGL1.
Biochemical and biophysical research communications
Mori K,Suzuki T,Miura K,Dohmae N,Simizu S
Wed Jun 30 00:00:00 EDT 2021
PLOD3 Is Associated with Immune Cell Infiltration and Genomic Instability in Colon Adenocarcinoma.
BioMed research international
Deng X,Pan Y,Yang M,Liu Y,Li J
Mon Oct 18 00:00:00 EDT 2021
p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi.
Science advances
Tan X,Banerjee P,Shi L,Xiao GY,Rodriguez BL,Grzeskowiak CL,Liu X,Yu J,Gibbons DL,Russell WK,Creighton CJ,Kurie JM
Tue Jun 01 00:00:00 EDT 2021
A Human Pan-Cancer System Analysis of Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3).
International journal of molecular sciences
Gong S,Duan Y,Wu C,Osterhoff G,Schopow N,Kallendrusch S
Tue Sep 14 00:00:00 EDT 2021
Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.
Glycobiology
Jia W,Zou X,Xu Z,Bai L,Shan A,Li Y,Shi J,Yang F,Ding C,Narimatsu H,Zhang Y
Thu Sep 09 00:00:00 EDT 2021
Mutations in PLOD3, encoding lysyl hydroxylase 3, cause a complex connective tissue disorder including recessive dystrophic epidermolysis bullosa-like blistering phenotype with abnormal anchoring fibrils and type VII collagen deficiency.
Matrix biology : journal of the International Society for Matrix Biology
Vahidnezhad H,Youssefian L,Saeidian AH,Touati A,Pajouhanfar S,Baghdadi T,Shadmehri AA,Giunta C,Kraenzlin M,Syx D,Malfait F,Has C,Lwin SM,Karamzadeh R,Liu L,Guy A,Hamid M,Kariminejad A,Zeinali S,McGrath JA,Uitto J
Thu Aug 01 00:00:00 EDT 2019
Mutations in PLOD3, encoding lysyl hydroxylase 3, cause a complex connective tissue disorder including recessive dystrophic epidermolysis bullosa-like blistering phenotype with abnormal anchoring fibrils and type VII collagen deficiency.
Matrix biology : journal of the International Society for Matrix Biology
Vahidnezhad H,Youssefian L,Saeidian AH,Touati A,Pajouhanfar S,Baghdadi T,Shadmehri AA,Giunta C,Kraenzlin M,Syx D,Malfait F,Has C,Lwin SM,Karamzadeh R,Liu L,Guy A,Hamid M,Kariminejad A,Zeinali S,McGrath JA,Uitto J
Thu Aug 01 00:00:00 EDT 2019
Overexpression of LH3 reduces the incidence of hypertensive intracerebral hemorrhage in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Li H,Xu H,Wen H,Liu T,Sun Y,Xiao N,Bai C,Ge J,Wang X,Song L,Song Y,Zhang Y,Chen J
Fri Mar 01 00:00:00 EST 2019
Overexpression of LH3 reduces the incidence of hypertensive intracerebral hemorrhage in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Li H,Xu H,Wen H,Liu T,Sun Y,Xiao N,Bai C,Ge J,Wang X,Song L,Song Y,Zhang Y,Chen J
Fri Mar 01 00:00:00 EST 2019
Overexpression of LH3 reduces the incidence of hypertensive intracerebral hemorrhage in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Li H,Xu H,Wen H,Liu T,Sun Y,Xiao N,Bai C,Ge J,Wang X,Song L,Song Y,Zhang Y,Chen J
Fri Mar 01 00:00:00 EST 2019
Overexpression of LH3 reduces the incidence of hypertensive intracerebral hemorrhage in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Li H,Xu H,Wen H,Liu T,Sun Y,Xiao N,Bai C,Ge J,Wang X,Song L,Song Y,Zhang Y,Chen J
Fri Mar 01 00:00:00 EST 2019
Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects.
Disease models & mechanisms
Geister KA,Lopez-Jimenez AJ,Houghtaling S,Ho TH,Vanacore R,Beier DR
Mon Jun 17 00:00:00 EDT 2019
Role of Glycosyltransferase 25 Domain 1 in Type I Collagen Glycosylation and Molecular Phenotypes.
Biochemistry
Terajima M,Taga Y,Sricholpech M,Kayashima Y,Sumida N,Maeda N,Hattori S,Yamauchi M
Tue Dec 17 00:00:00 EST 2019
Identification and characterization of collagen-like glycosylation and hydroxylation of CCN1.
Glycobiology
Ishizawa Y,Niwa Y,Suzuki T,Kawahara R,Dohmae N,Simizu S
Fri Sep 20 00:00:00 EDT 2019
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
PLoS genetics
Terajima M,Taga Y,Cabral WA,Liu Y,Nagasawa M,Sumida N,Kayashima Y,Chandrasekaran P,Han L,Maeda N,Perdivara I,Hattori S,Marini JC,Yamauchi M
Sat Jun 01 00:00:00 EDT 2019
PLOD3 suppression exerts an anti-tumor effect on human lung cancer cells by modulating the PKC-delta signaling pathway.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Lee J,Kim JY,Jo Y,Cho JM,Lee CW,Song JY,Ahn J,Kim JS,Kim EH,Hwang SG
Fri Feb 15 00:00:00 EST 2019
PLOD3 suppression exerts an anti-tumor effect on human lung cancer cells by modulating the PKC-delta signaling pathway.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Lee J,Kim JY,Jo Y,Cho JM,Lee CW,Song JY,Ahn J,Kim JS,Kim EH,Hwang SG
Fri Feb 15 00:00:00 EST 2019
PLOD3 promotes lung metastasis via regulation of STAT3.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Kim JY,Lee CW,Song JY,Um HD,Kang CM,Park JK,Kim JS,Kim EH,Hwang SG
Thu Nov 15 00:00:00 EST 2018
PLOD3 promotes lung metastasis via regulation of STAT3.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Kim JY,Lee CW,Song JY,Um HD,Kang CM,Park JK,Kim JS,Kim EH,Hwang SG
Thu Nov 15 00:00:00 EST 2018
PLOD3 promotes lung metastasis via regulation of STAT3.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Kim JY,Lee CW,Song JY,Um HD,Kang CM,Park JK,Kim JS,Kim EH,Hwang SG
Thu Nov 15 00:00:00 EST 2018
PLOD3 promotes lung metastasis via regulation of STAT3.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Kim JY,Lee CW,Song JY,Um HD,Kang CM,Park JK,Kim JS,Kim EH,Hwang SG
Thu Nov 15 00:00:00 EST 2018
PLOD3 promotes lung metastasis via regulation of STAT3.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Kim JY,Lee CW,Song JY,Um HD,Kang CM,Park JK,Kim JS,Kim EH,Hwang SG
Thu Nov 15 00:00:00 EST 2018
PLOD3 promotes lung metastasis via regulation of STAT3.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Kim JY,Lee CW,Song JY,Um HD,Kang CM,Park JK,Kim JS,Kim EH,Hwang SG
Thu Nov 15 00:00:00 EST 2018
PLOD3 promotes lung metastasis via regulation of STAT3.
Cell death & disease
Baek JH,Yun HS,Kwon GT,Kim JY,Lee CW,Song JY,Um HD,Kang CM,Park JK,Kim JS,Kim EH,Hwang SG
Thu Nov 15 00:00:00 EST 2018
Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nature communications
Scietti L,Chiapparino A,De Giorgi F,Fumagalli M,Khoriauli L,Nergadze S,Basu S,Olieric V,Cucca L,Banushi B,Profumo A,Giulotto E,Gissen P,Forneris F
Wed Aug 08 00:00:00 EDT 2018
Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nature communications
Scietti L,Chiapparino A,De Giorgi F,Fumagalli M,Khoriauli L,Nergadze S,Basu S,Olieric V,Cucca L,Banushi B,Profumo A,Giulotto E,Gissen P,Forneris F
Wed Aug 08 00:00:00 EDT 2018
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Journal of molecular and cellular cardiology
Cowling RT,Park JI,Sotimehin AE,Greenberg BH
Fri Dec 01 00:00:00 EST 2017
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Journal of molecular and cellular cardiology
Cowling RT,Park JI,Sotimehin AE,Greenberg BH
Fri Dec 01 00:00:00 EST 2017
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Journal of molecular and cellular cardiology
Cowling RT,Park JI,Sotimehin AE,Greenberg BH
Fri Dec 01 00:00:00 EST 2017
Radiotherapy diagnostic biomarkers in radioresistant human H460 lung cancer stem-like cells.
Cancer biology & therapy
Yun HS,Baek JH,Yim JH,Um HD,Park JK,Song JY,Park IC,Kim JS,Lee SJ,Lee CW,Hwang SG
Tue Dec 13 00:00:00 EST 2016
Radiotherapy diagnostic biomarkers in radioresistant human H460 lung cancer stem-like cells.
Cancer biology & therapy
Yun HS,Baek JH,Yim JH,Um HD,Park JK,Song JY,Park IC,Kim JS,Lee SJ,Lee CW,Hwang SG
Tue Dec 13 00:00:00 EST 2016
Localization of collagen modifying enzymes on fibroblastic reticular cells and follicular dendritic cells in non-neoplastic and neoplastic lymphoid tissues.
Leukemia & lymphoma
Ohe R,Aung NY,Meng H,Kabasawa T,Suto A,Tamazawa N,Yang S,Kato T,Yamakawa M
Fri Jul 01 00:00:00 EDT 2016
Localization of collagen modifying enzymes on fibroblastic reticular cells and follicular dendritic cells in non-neoplastic and neoplastic lymphoid tissues.
Leukemia & lymphoma
Ohe R,Aung NY,Meng H,Kabasawa T,Suto A,Tamazawa N,Yang S,Kato T,Yamakawa M
Fri Jul 01 00:00:00 EDT 2016
Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis.
Nature communications
Banushi B,Forneris F,Straatman-Iwanowska A,Strange A,Lyne AM,Rogerson C,Burden JJ,Heywood WE,Hanley J,Doykov I,Straatman KR,Smith H,Bem D,Kriston-Vizi J,Ariceta G,Risteli M,Wang C,Ardill RE,Zaniew M,Latka-Grot J,Waddington SN,Howe SJ,Ferraro F,Gjinovci A,Lawrence S,Marsh M,Girolami M,Bozec L,Mills K,Gissen P
Wed Jul 20 00:00:00 EDT 2016
Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis.
Nature communications
Banushi B,Forneris F,Straatman-Iwanowska A,Strange A,Lyne AM,Rogerson C,Burden JJ,Heywood WE,Hanley J,Doykov I,Straatman KR,Smith H,Bem D,Kriston-Vizi J,Ariceta G,Risteli M,Wang C,Ardill RE,Zaniew M,Latka-Grot J,Waddington SN,Howe SJ,Ferraro F,Gjinovci A,Lawrence S,Marsh M,Girolami M,Bozec L,Mills K,Gissen P
Wed Jul 20 00:00:00 EDT 2016
Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis.
Nature communications
Banushi B,Forneris F,Straatman-Iwanowska A,Strange A,Lyne AM,Rogerson C,Burden JJ,Heywood WE,Hanley J,Doykov I,Straatman KR,Smith H,Bem D,Kriston-Vizi J,Ariceta G,Risteli M,Wang C,Ardill RE,Zaniew M,Latka-Grot J,Waddington SN,Howe SJ,Ferraro F,Gjinovci A,Lawrence S,Marsh M,Girolami M,Bozec L,Mills K,Gissen P
Wed Jul 20 00:00:00 EDT 2016
Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis.
Nature communications
Banushi B,Forneris F,Straatman-Iwanowska A,Strange A,Lyne AM,Rogerson C,Burden JJ,Heywood WE,Hanley J,Doykov I,Straatman KR,Smith H,Bem D,Kriston-Vizi J,Ariceta G,Risteli M,Wang C,Ardill RE,Zaniew M,Latka-Grot J,Waddington SN,Howe SJ,Ferraro F,Gjinovci A,Lawrence S,Marsh M,Girolami M,Bozec L,Mills K,Gissen P
Wed Jul 20 00:00:00 EDT 2016
Lysyl Hydroxylase 3 Localizes to Epidermal Basement Membrane and Is Reduced in Patients with Recessive Dystrophic Epidermolysis Bullosa.
PloS one
Watt SA,Dayal JH,Wright S,Riddle M,Pourreyron C,McMillan JR,Kimble RM,Prisco M,Gartner U,Warbrick E,McLean WH,Leigh IM,McGrath JA,Salas-Alanis JC,Tolar J,South AP
Tue May 31 00:00:00 EDT 2016
Lysyl Hydroxylase 3 Localizes to Epidermal Basement Membrane and Is Reduced in Patients with Recessive Dystrophic Epidermolysis Bullosa.
PloS one
Watt SA,Dayal JH,Wright S,Riddle M,Pourreyron C,McMillan JR,Kimble RM,Prisco M,Gartner U,Warbrick E,McLean WH,Leigh IM,McGrath JA,Salas-Alanis JC,Tolar J,South AP
Tue May 31 00:00:00 EDT 2016
Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation.
The Journal of biological chemistry
Dayer C,Stamenkovic I
Fri May 29 00:00:00 EDT 2015
Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation.
The Journal of biological chemistry
Dayer C,Stamenkovic I
Fri May 29 00:00:00 EDT 2015
Deregulation of the lysyl hydroxylase matrix cross-linking system in experimental and clinical bronchopulmonary dysplasia.
American journal of physiology. Lung cellular and molecular physiology
Witsch TJ,Turowski P,Sakkas E,Niess G,Becker S,Herold S,Mayer K,Vadász I,Roberts JD,Seeger W,Morty RE
Sat Feb 01 00:00:00 EST 2014
Deregulation of the lysyl hydroxylase matrix cross-linking system in experimental and clinical bronchopulmonary dysplasia.
American journal of physiology. Lung cellular and molecular physiology
Witsch TJ,Turowski P,Sakkas E,Niess G,Becker S,Herold S,Mayer K,Vadász I,Roberts JD,Seeger W,Morty RE
Sat Feb 01 00:00:00 EST 2014
Deregulation of the lysyl hydroxylase matrix cross-linking system in experimental and clinical bronchopulmonary dysplasia.
American journal of physiology. Lung cellular and molecular physiology
Witsch TJ,Turowski P,Sakkas E,Niess G,Becker S,Herold S,Mayer K,Vadász I,Roberts JD,Seeger W,Morty RE
Sat Feb 01 00:00:00 EST 2014
Deregulation of the lysyl hydroxylase matrix cross-linking system in experimental and clinical bronchopulmonary dysplasia.
American journal of physiology. Lung cellular and molecular physiology
Witsch TJ,Turowski P,Sakkas E,Niess G,Becker S,Herold S,Mayer K,Vadász I,Roberts JD,Seeger W,Morty RE
Sat Feb 01 00:00:00 EST 2014
Abnormal type I collagen post-translational modification and crosslinking in a cyclophilin B KO mouse model of recessive osteogenesis imperfecta.
PLoS genetics
Cabral WA,Perdivara I,Weis M,Terajima M,Blissett AR,Chang W,Perosky JE,Makareeva EN,Mertz EL,Leikin S,Tomer KB,Kozloff KM,Eyre DR,Yamauchi M,Marini JC
Sun Jun 01 00:00:00 EDT 2014
Abnormal type I collagen post-translational modification and crosslinking in a cyclophilin B KO mouse model of recessive osteogenesis imperfecta.
PLoS genetics
Cabral WA,Perdivara I,Weis M,Terajima M,Blissett AR,Chang W,Perosky JE,Makareeva EN,Mertz EL,Leikin S,Tomer KB,Kozloff KM,Eyre DR,Yamauchi M,Marini JC
Sun Jun 01 00:00:00 EDT 2014
Lysyl hydroxylase 3 is secreted from cells by two pathways.
Journal of cellular physiology
Wang C,Ristiluoma MM,Salo AM,Eskelinen S,Myllylä R
Wed Feb 01 00:00:00 EST 2012
Lysyl hydroxylase 3 is secreted from cells by two pathways.
Journal of cellular physiology
Wang C,Ristiluoma MM,Salo AM,Eskelinen S,Myllylä R
Wed Feb 01 00:00:00 EST 2012
Proteomic dissection of the von Hippel-Lindau (VHL) interactome.
Journal of proteome research
Lai Y,Song M,Hakala K,Weintraub ST,Shiio Y
Fri Nov 04 00:00:00 EDT 2011
Proteomic dissection of the von Hippel-Lindau (VHL) interactome.
Journal of proteome research
Lai Y,Song M,Hakala K,Weintraub ST,Shiio Y
Fri Nov 04 00:00:00 EDT 2011
Characterisation of the Drosophila procollagen lysyl hydroxylase, dPlod.
Gene expression patterns : GEP
Bunt S,Denholm B,Skaer H
Thu Mar 24 00:00:00 EDT 2011
Characterisation of the Drosophila procollagen lysyl hydroxylase, dPlod.
Gene expression patterns : GEP
Bunt S,Denholm B,Skaer H
Thu Mar 24 00:00:00 EDT 2011
The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability.
Journal of cellular and molecular medicine
Wang C,Kovanen V,Raudasoja P,Eskelinen S,Pospiech H,Myllylä R
Sun Mar 01 00:00:00 EST 2009
The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability.
Journal of cellular and molecular medicine
Wang C,Kovanen V,Raudasoja P,Eskelinen S,Pospiech H,Myllylä R
Sun Mar 01 00:00:00 EST 2009
Reduction of lysyl hydroxylase 3 causes deleterious changes in the deposition and organization of extracellular matrix.
The Journal of biological chemistry
Risteli M,Ruotsalainen H,Salo AM,Sormunen R,Sipilä L,Baker NL,Lamandé SR,Vimpari-Kauppinen L,Myllylä R
Fri Oct 09 00:00:00 EDT 2009
Reduction of lysyl hydroxylase 3 causes deleterious changes in the deposition and organization of extracellular matrix.
The Journal of biological chemistry
Risteli M,Ruotsalainen H,Salo AM,Sormunen R,Sipilä L,Baker NL,Lamandé SR,Vimpari-Kauppinen L,Myllylä R
Fri Oct 09 00:00:00 EDT 2009
A connective tissue disorder caused by mutations of the lysyl hydroxylase 3 gene.
American journal of human genetics
Salo AM,Cox H,Farndon P,Moss C,Grindulis H,Risteli M,Robins SP,Myllylä R
Wed Oct 01 00:00:00 EDT 2008
A connective tissue disorder caused by mutations of the lysyl hydroxylase 3 gene.
American journal of human genetics
Salo AM,Cox H,Farndon P,Moss C,Grindulis H,Risteli M,Robins SP,Myllylä R
Wed Oct 01 00:00:00 EDT 2008