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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.; FUNCTION: Isoform 1 has no prospholipid scramblase activity, due to the lack of a N-terminal proline-rich domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ca(2+)-dependent phospholipid scramblase 2; Phospholipid scramblase 2; PL scramblase 2
Gene Aliases: PLSCR2
UniProt ID: (Human) Q9NRY7, (Mouse) Q9DCW2
Entrez Gene ID: (Human) 57047, (Mouse) 18828
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