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Abnova
PLSCR3 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 3
PLSCR3 Antibody (H00057048-D01P) in WB
Western Blot analysis of PLSCR3 expression in transfected 293T cell line (H00057048-T02) by PLSCR3 MaxPab polyclonal antibody.
Lane 1: PLSCR3 transfected lysate(31.70 KDa).
Lane 2: Non-transfected lysate.
Lane 1: PLSCR3 transfected lysate(31.70 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00057048-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLSCR3 (AAH11735.1, 1 a.a. approximately 295 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MAGYLPPKGY APSPPPPYPV TPGYPEPALH PGPGQAPVPA QVPAPAPGFA LFPSPGPVAL GSAAPFLPLP GVPSGLEFLV QIDQILIHQK AERVETFLGW ETCNRYELRS GAGQPLGQAA EESNCCARLC CGARRPLRVR LADPGDRELL RLLRPLHCGC SCCPCGLQEM EVQAPPGTTI GHVLQTWHPF LPKFSIQDAD RQTVLRVVGP CWTCGCGTDT NFEVKTRDES RSVGRISKQW GGLVREALTD ADDFGLQFPL DLDVRVKAVL LGATFLIDYM FFEKRGGAGP SAITS
Target Information
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca 2+ dependent phospholipid scramblase 3; Ca(2+)-dependent phospholipid scramblase 3; Phospholipid scramblase 3; PL scramblase 3
Gene Aliases: 2210403O21Rik; 2610037N06Rik; ESTM3; PLSCR3; X83310
UniProt ID: (Human) Q9NRY6, (Mouse) Q9JIZ9
Entrez Gene ID: (Human) 57048, (Mouse) 70310
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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