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Invitrogen
PLUNC Polyclonal Antibody
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Product Details
PA5-99874
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human BPIFA1(Accession Q9NP55), corresponding to amino acid residues T143-D193.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PLUNC.
Target Information
PLUNC is the human homolog of murine plunc and is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this protein is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only two is known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BPI fold-containing family A member 1; ES cell-related protein; ligand-binding protein RYA3; LPLUNC3; Lung-specific protein X; LUNX; LUNXNASG; Nasopharyngeal carcinoma-related protein; Palate lung and nasal epithelium clone protein; palate, lung and nasal epithelium associated; palate, lung, and nasal epithelium carcinoma associated protein; palate, lung, and nasal epithelium expressed transcript; protein Plunc; Secretory protein in upper respiratory tracts; short palate; Short PLUNC1; SPLUNC1; SPLUNC1SPURT; SpurtA; tracheal epithelium enriched protein; Tracheal epithelium-enriched protein; unnamed protein product; Von Ebner protein Hl
Gene Aliases: bA49G10.5; BPIFA1; LUNX; NASG; PLUNC; SPLUNC1; SPURT; UNQ787/PRO1606
UniProt ID: (Human) Q9NP55, (Rat) Q8K4I4
Entrez Gene ID: (Human) 51297, (Rat) 246238
antibacterial humoral response
innate immune response
regulation of liquid surface tension
multicellular organismal water homeostasis
negative regulation of single-species biofilm formation in or on host organism
regulation of sodium ion transmembrane transport
immune system process
immune response in nasopharyngeal-associated lymphoid tissue
defense response to bacterium
surfactant homeostasis
defense response to virus
antimicrobial humoral immune response mediated by antimicrobial peptide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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