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Invitrogen
PLXNB2 Polyclonal Antibody
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Product Details
PA5-51824
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLXNB2. Recombinant protein control fragment (Product #RP-91533).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DSPSNKLLYA KEISTYKKMV EDYYKGIRQM VQVSDQDMNT HLAEISRAHT DSLNTLVALH QLYQYTQKYY DEIINALEED PAAQKMQLAF RLQQIAAALE NKVTD
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved converting the single chain precursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MM1; MM1KIAA0315dJ402G11.3; Plexin-B2
Gene Aliases: dJ402G11.3; KIAA0315; MM1; Nbla00445; PLEXB2; PLXNB2
UniProt ID: (Human) O15031
Entrez Gene ID: (Human) 23654
neural tube closure
regulation of protein phosphorylation
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
neuroblast proliferation
brain development
regulation of cell shape
positive regulation of neuron projection development
regulation of cell migration
regulation of GTPase activity
positive regulation of axonogenesis
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in axon guidance
regulation of neuron migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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