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Invitrogen
PMAT Polyclonal Antibody
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Product Details
PA5-50877
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to a region derived from internal residues of human solute carrier family 29 (equilibrative nucleoside transporter), member 4
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total PMAT protein.
Target Information
PMAT(Slc29a4) is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the re-uptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Equilibrative nucleoside transporter 4; FLJ34923; hENT4; Plasma membrane monoamine transporter; PMAT; solute carrier family 29 (equilibrative nucleoside transporter), member 4; solute carrier family 29 (nucleoside transporters), member 4; Solute carrier family 29 member 4; unnamed protein product
Gene Aliases: ENT4; PMAT; PSEC0113; SLC29A4
UniProt ID: (Human) Q7RTT9
Entrez Gene ID: (Human) 222962
neurotransmitter transporter activity
nucleoside transmembrane transporter activity
organic acid transmembrane transporter activity
cation transmembrane transporter activity
monoamine transmembrane transporter activity
organic cation transmembrane transporter activity
efflux transmembrane transporter activity
toxin transporter activity
xenobiotic transporter activity
histamine metabolic process
neurotransmitter transport
serotonin transport
organic cation transport
monoamine transport
dopamine transport
norepinephrine transport
adenosine transport
xenobiotic transport
epinephrine transport
histamine transport
serotonin uptake
histamine uptake
norepinephrine uptake
epinephrine uptake
dopamine uptake
cation transmembrane transport
export across plasma membrane
transport across blood-brain barrier
nucleoside transmembrane transport
organic acid transmembrane transport
cellular detoxification
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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