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Invitrogen
PMCH Polyclonal Antibody
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FIGURE: 1 / 7
PMCH Antibody (PA5-84521) in IHC (P)
Immunohistochemistry analysis of PMCH in human cerebral cortex, hypothalamus, liver and testis. Samples were incubated with PMCH polyclonal antibody (Product # PA5-84521). Shows similar protein distribution across tissues to independent PMCH antibody (Product # PA5-83802) (B).
Product Details
PA5-84521
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PMCH. Recombinant protein control fragment (Product #RP-107107).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KGSVAFPAEN GVQNTESTQE KREIGDEENS AKFPIGRRDF DMLRCMLGRV YRPCW
Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 98%.
Target Information
MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neuropeptide-glutamic acid-isoleucine (NEI); neuropeptide-glycine-glutamic acid (NGE); prepro-MCH; prepro-melanin-concentrating hormone; Pro-MCH; pro-melanin-concentrating hormone
Gene Aliases: A230109K23Rik; MCH; PMCH; ppMCH
UniProt ID: (Human) P20382, (Mouse) P56942
Entrez Gene ID: (Human) 5367, (Mouse) 110312
neuropeptide signaling pathway
chemical synaptic transmission
multicellular organism development
spermatogenesis
feeding behavior
cell differentiation
regulation of heart rate
positive regulation of cytosolic calcium ion concentration
response to cold
negative regulation of synaptic transmission, dopaminergic
glucose homeostasis
drinking behavior
negative regulation of blood pressure
positive regulation of circadian sleep/wake cycle, REM sleep
regulation of neuronal synaptic plasticity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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