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Invitrogen
PMEPA1 Polyclonal Antibody
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FIGURE: 1 / 2
PMEPA1 Antibody (PA5-75980) in WB
Western blot analysis of PMEPA1 in Lane 1: HeLa whole cell lysate (40 µg), Lane 2: PC3 whole cell lysate (40 µg), Lane 3: the uterus tissue lysate of mouse (40 µg), Lane 4: the testis tissue lysate of rat (40 µg). Samples were incubated with PMEPA1 polyclonal antibody (Product # PA5-75980) at a dilution of 1:500.
Product Details
PA5-75980
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 115-159 of Human PMEPA1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 100% (by SDS-PAGE).
Target Information
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Nedd4 WW binding protein 4; NEDD4 WW domain-binding protein 4; Prostate transmembrane protein androgen induced 1; Protein TMEPAI; Solid tumor-associated 1 protein; solid tumor-associated gene 1; Transmembrane prostate androgen-induced protein; transmembrane, prostate androgen induced RNA; type 1b transmembrane protein; unknown function; unnamed protein product
Gene Aliases: 2210418I02Rik; AW455466; Erg1.2; N4wbp4; PMEPA1; STAG1; TMEPAI
UniProt ID: (Human) Q969W9
Entrez Gene ID: (Human) 56937, (Rat) 311676, (Mouse) 65112
negative regulation of signal transduction
negative regulation of transforming growth factor beta receptor signaling pathway
androgen receptor signaling pathway
negative regulation of SMAD protein import into nucleus
biological_process
negative regulation of SMAD protein complex assembly
negative regulation of pathway-restricted SMAD protein phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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