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Invitrogen
PML-5 Polyclonal Antibody
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Product Details
PA5-120613
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 300-600 of human PML (NP_1502412)
Conjugate
Form
Liquid
Concentration
0.88 mg/mL
Amount
88 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: Rat spleen, Rat lung, Rat kidney. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Early endosome membrane, Endoplasmic reticulum membrane, Nucleus, PML body, Peripheral membrane protein, nucleolus, nucleoplasm.
Immunogen sequence: AVDARYQRDY EEMASRLGRL DAVLQRIRTG SALVQRMKCY ASDQEVLDMH GFLRQALCRL RQEEPQSLQA AVRTDGFDEF KVRLQDLSSC ITQGKDAAVS KKASPEAAST PRDPIDVDLP EEAERVKAQV QALGLAEAQP MAVVQSVPGA HPVPVYAFSI KGPSYGEDVS NTTTAQKRKC SQTQCPRKVI KMESEEGKEA RLARSSPEQP RPSTSKAVSP PHLDGPPSPR SPVIGSEVFL PNSNHVASGA GEAEERVVVI SSSEDSDAEN SSSRELDDSS SESSDLQLEG PSTLRVLDEN L
Target Information
Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions. [Uniprot]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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