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          • Primary Antibodies ›
          • PMS2 Antibodies

          NeoBiotechnologies

          PMS2 (Postmeiotic Segregation Increased 2) Recombinant Rabbit Monoclonal Antibody (PMS2/8374R)

          View all (42) PMS2 antibodies

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          Cite PMS2 (Postmeiotic Segregation Increased 2) Recombinant Rabbit Monoclonal Antibody (PMS2/8374R)

          • Antibody Testing Data (3)
          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          PMS2 (Postmeiotic Segregation Increased 2) Antibody (5395-RBM8-P0) in IHC (P)

          Formalin-fixed, paraffin-embedded human colon carcinoma stained with PMS2 Recombinant Rabbit Monoclonal Antibody (PMS2/8374R). HIER: Tris/EDTA, pH9.0, 45 min. 2: HRP-polymer, 30 min. DAB, 5 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PMS2 (Postmeiotic Segregation Increased 2) Antibody in SDS-PAGE (SDS-PAGE)
          PMS2 (Postmeiotic Segregation Increased 2) Recombinant Rabbit Monoclonal Antibody (PMS2/8374R)

          Product Details

          5395-RBM8-P0

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          Assay-dependent
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG, kappa

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          PMS2/8374R

          Immunogen

          Recombinant fragment (around aa1-200) of human PMS2 protein.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          200 µg/mL

          Purification

          Protein A/G

          Storage buffer

          PBS, pH 7.4, with 0.05% BSA

          Contains

          0.05% sodium azide

          Storage conditions

          4°C, do not freeze

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is an amino acid protein of 862 amino acids.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: DNA mismatch repair protein PMS2; H_DJ0042M02.9; Mismatch repair endonuclease PMS2; PMS1 homolog 2, mismatch repair protein; PMS1 protein homolog 2; PMS2 postmeiotic segregation increased 2; postmeiotic segregation increased 2 nirs variant 6

          View more View less

          Gene Aliases: HNPCC4; MLH4; PMS2; PMS2CL; PMSL2

          View more View less

          UniProt ID: (Human) P54278

          View more View less

          Entrez Gene ID: (Human) 5395

          View more View less

          Function(s)
          DNA binding single-stranded DNA binding endonuclease activity protein binding ATP binding ATPase activity single base insertion or deletion binding MutSalpha complex binding DNA metabolism protein
          Process(es)
          mismatch repair somatic hypermutation of immunoglobulin genes response to drug nucleic acid phosphodiester bond hydrolysis
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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