3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HsPNLDC1; PARN-like domain-containing protein 1; PNLDC1; poly(A)-specific ribonuclease (PARN)-like domain containing 1; Poly(A)-specific ribonuclease domain-containing protein 1; Poly(A)-specific ribonuclease PNLDC1
Gene Aliases: PNLDC1
UniProt ID: (Human) Q8NA58
Entrez Gene ID: (Human) 154197