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Proteintech
PNMT Polyclonal Antibody
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Product Details
13217-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PNMT Fusion Protein Ag4098 (1-282 aa encoded by BC037246)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSGADRSPN AGAAPDSAPG QAAVASAYQR FEPRAYLRNN YAPPRGDLCN PNGVGPWKLR CLAQTFATGE VSGRTLIDIG SGPTVYQLLS ACSHFEDITM TDFLEVNRQE LGRWLQEEPG AFNWSMYSQH ACLIEGKGEC WQDKERQLRA RVKRVLPIDV HQPQPLGAGS PAPLPADALV SAFCLEAVSP DLASFQRALD HITTLLRPGG HLLLIGALEE SWYLAGEARL TVVPVSEEEV REALVRSGYK VRDLRTYIMP AHLQTGVDDV KGVFFAWAQK VGL (1-282 aa encoded by BC037246)
Target Information
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Noradrenaline N-methyltransferase; phenylethanolamine N-methylase; Phenylethanolamine N-methyltransferase; PNMT; PNMTase
Gene Aliases: PENT; PNMT; PNMTase
UniProt ID: (Human) P11086, (Mouse) P40935, (Rat) P10937
Entrez Gene ID: (Human) 5409, (Mouse) 18948, (Rat) 24661
methylation
epinephrine biosynthetic process
catecholamine biosynthetic process
norepinephrine metabolic process
response to hypoxia
response to cold
response to water deprivation
response to activity
adrenal gland development
response to corticosteroid
response to insulin
social behavior
response to isolation stress
response to immobilization stress
response to peptide hormone
response to ethanol
response to ether
S-adenosylhomocysteine metabolic process
S-adenosylmethionine metabolic process
sensory perception of taste
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to dexamethasone stimulus
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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