Immunogen sequence: DSGWLKQKNI KQAIKSLKKY SDKSAEKSPF PEEKSHIIDK EEDIGKRSLF HYTSSITTKF GDSFYFLSNH INSYFKRKEK MSQQKENE
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 69%.
Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calcium-independent phospholipase A2-gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2-2; iPLA2-gamma; membrane-associated calcium-independent phospholipase A2 gamma; patatin-like phospholipase domain containing 8; Patatin-like phospholipase domain-containing protein 8; PNPLA-gamma
Gene Aliases: BM-043; IPLA2-2; IPLA22; IPLA2G; iPLA2gamma; MMLA; PNPLA-gamma; PNPLA8
UniProt ID: (Human) Q9NP80
Entrez Gene ID: (Human) 50640