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          • Primary Antibodies ›
          • POC1A Antibodies

          Invitrogen

          POC1A Polyclonal Antibody

          2 References
          View all (6) POC1A antibodies

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          Cite POC1A Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (5)
          POC1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          POC1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 5

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          POC1A Antibody (PA5-59217) in IHC (P)

          Immunohistochemical analysis of POC1A in human placenta using POC1A Polyclonal Antibody (Product # PA5-59217) shows moderate granular cytoplasmic positivity in trophoblastic cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          POC1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          POC1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          POC1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          POC1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          POC1A Antibody in Western Blot (WB)
          POC1A Polyclonal Antibody

          Product Details

          PA5-59217

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human POC1A. Recombinant protein control fragment (Product #RP-98202).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2645730

          Product Specific Information

          Immunogen sequence: RLLYTLHGHQ GPATTVAFSR TGEYFASGGS DEQVMVWKSN FDIVDHGEVT KVPRPPATLA SSMGNLPEVD FPVPPGRGRS VESVQSQPQE PVSVPQTLTS TLEH

          Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

          Target Information

          POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Pix2; POC1 centriolar protein homolog A; Proteome of centriole protein 1A; unnamed protein product; WD repeat domain 51A; WD repeat-containing protein 51A

          View more View less

          Gene Aliases: PIX2; POC1A; SOFT; WDR51A

          View more View less

          UniProt ID: (Human) Q8NBT0

          View more View less

          Entrez Gene ID: (Human) 25886

          View more View less

          Function(s)
          protein binding
          Process(es)
          growth plate cartilage chondrocyte development mitotic spindle organization spermatogenesis positive regulation of centrosome duplication cell projection organization cilium morphogenesis bone development non-motile cilium assembly
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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