PA5-28116 targets PODXL in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-28116 immunogen is synthetic peptide corresponding to a region within amino acids 436 and 530 of Human PODXL.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
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Protein Aliases: GCTM-2 antigen; Gp200; PC; PCLP; PCLP-1; Podocalyxin; podocalyxin-like; Podocalyxin-like protein 1
Gene Aliases: AW121214; Gp200; Ly102; PC; PCLP; PCLP-1; PCLP1; PODXL