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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:3,000 | View 3 publications 3 publications |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
POLD1 Fusion Protein Ag8178 (858-1107 aa encoded by BC008800) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: EGAVAHAQD VISDLLCNRI DISQLVITKE LTRAASDYAG KQAHVELAER MRKRDPGSAP SLGDRVPYVI ISAAKGVAAY MKSEDPLFVL EHSLPIDTQY YLEQQLAKPL LRIFEPILGE GRAEAVLLRG DHTRCKTVLT GKVGGLLAFA KRRNCCIGCR TVLSHQGAVC EFCQPRESEL YQKEVSHLNA LEERFSRLWT QCQRCQGSLH EDVICTSRDC PIFYMRKKVR KDLEDQEQLL RRFGPPGPEA W (858-1107 aa encoded by BC008800)
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3'-5' exodeoxyribonuclease; CDC2 homolog; DNA polymerase delta 1, catalytic domain; DNA polymerase delta catalytic subunit; DNA polymerase delta, catalytic subunit; DNA polymerase subunit delta p125; DNA-directed DNA polymerase delta 1; POL D; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; polymerase (DNA) delta 1, catalytic subunit; Polymerase D
Gene Aliases: 125kDa; CDC2; CRCS10; MDPL; POLD; POLD1
UniProt ID: (Human) P28340, (Rat) O54747, (Mouse) P52431
Entrez Gene ID: (Human) 5424, (Rat) 59294, (Mouse) 18971
Molecular Function:
DNA metabolism protein
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