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POLD4 Antibody (PA5-103790) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded POLD4 in human kidney tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with POLD4 polyclonal antibody (Product # PA5-103790) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-103790
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human POLD4(Accession Q9HCU8), corresponding to amino acid residues P38-R66.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
RRID
AB_2853123
Target Information
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA polymerase delta smallest subunit p12; DNA polymerase delta subunit 4; DNA polymerase delta subunit p12; polymerase (DNA) delta 4, accessory subunit; polymerase (DNA-directed), delta 4, accessory subunit
Gene Aliases: p12; POLD4; POLDS
UniProt ID: (Human) Q9HCU8
Entrez Gene ID: (Human) 57804
Molecular Function:
DNA metabolism protein
DNA-directed DNA polymerase
nucleic acid metabolism protein
telomere maintenance via recombination
telomere maintenance
DNA synthesis involved in DNA repair
DNA replication
DNA-dependent DNA replication
DNA strand elongation involved in DNA replication
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
mismatch repair
translesion synthesis
nucleotide-excision repair, DNA incision
DNA damage response, detection of DNA damage
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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