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Product Details
H00005426-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
POLE (AAH21559, 1 a.a. approximately 370 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).^M
^M
The Isotype of this product is composed of an IgG Mixture.^M
^M
Immunogen sequence: MDPSNYGGIK GKVSSRIHCG LQDSQKAGGA EDEQENEDDE EERDGEEEEE AEESNVEDLL ENNWNILQFL PQAASCQNYF LMIVSAYIVA VYHCMKDGLR RSAPGSTPVR RRGASQLSQE AEGAVGALPG MITFSQDYVA NELTQSFFTI TQKIQKKVTG SRNSTELSEM FPVLPGSHLL LNNPALEFIK YVCKVLSLDT NITNQVNKLN RDLLRLVDVG EFSEEAQFRD PCRSYVLPEV ICRSCNFCRD LDLCKDSSFS EDGAVLPQWL CSNCQAPYDS SAIEMTLVEV LQKKLVAFTL QDLVCLKCRG VKETSMPVYC SCAGDFALTI HTQVFMEQIG IFRNIAQHYG MSYLLETLEW LLQKNPQLGH
Target Information
POLE (Polepsi) is present in proliferating cells and is implicated in repair of UV-damaged DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exodeoxyribonuclease; DNA polymerase epsilon catalytic subunit A; DNA polymerase epsilon catalytic subunit protein; DNA polymerase II subunit A; polymerase (DNA directed), epsilon, catalytic subunit; polymerase (DNA) epsilon, catalytic subunit
Gene Aliases: CRCS12; FILS; POLE; POLE1
UniProt ID: (Human) Q07864
Entrez Gene ID: (Human) 5426
G1/S transition of mitotic cell cycle
telomere maintenance via recombination
DNA synthesis involved in DNA repair
DNA replication
DNA replication initiation
base-excision repair, gap-filling
nucleotide-excision repair, DNA gap filling
embryonic organ development
nucleic acid phosphodiester bond hydrolysis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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