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Product Details
PA5-54721
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human POLG2. Recombinant protein control fragment (Product #RP-102236).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645748
Product Specific Information
Immunogen sequence: LDRGMLAYLY DSFQLTENSF TRKKNLHRKV LKLHPCLAPI KVALDVGRGP TLELRQVCQG LFNELLENGI SVWPGYLETM QSSLEQLYSK YDEMSILFTV LVTETTLENG LIHLRSRDTT MKE
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 89%.
Target Information
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA polymerase gamma accessory 55 kDa subunit; DNA polymerase subunit gamma-2; Mitochondrial DNA polymerase accessory subunit; mitochondrial DNA polymerase subunit gamma-2; mitochondrial DNA polymerase, accessory subunit; MtPolB; p55; PolG-beta; polymerase (DNA directed), gamma 2, accessory subunit; polymerase (DNA) gamma 2, accessory subunit
Gene Aliases: HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLG2; POLGB
UniProt ID: (Human) Q9UHN1
Entrez Gene ID: (Human) 11232
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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