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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA polymerase gamma accessory 55 kDa subunit; DNA polymerase subunit gamma-2; DNA polymerase subunit gamma-2, mitochondrial; Mitochondrial DNA polymerase accessory subunit; mitochondrial DNA polymerase subunit gamma-2; mitochondrial DNA polymerase, accessory subunit; mitochondrial polymerase gamma 2; MtPolB; p55; PolG-beta; polymerase (DNA directed), gamma 2, accessory subunit; polymerase (DNA) gamma 2, accessory subunit; polymerase, gamma 2
Gene Aliases: HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLG2; POLGB
UniProt ID: (Human) Q9UHN1, (Mouse) Q9QZM2
Entrez Gene ID: (Human) 11232, (Rat) 303612, (Mouse) 50776
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