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Proteintech
POLR1E Polyclonal Antibody
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Product Details
16145-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
POLR1E Fusion Protein Ag9269 (104-419 aa encoded by BC014331)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AELFNMQPL FSDVSVESEL ALESQTKTYR EKMDSCIEAF GTTKQKRALN TRRMNRVGNE SLNRAVAKAA ETIIDTKGVT ALVSDAIHND LQDDSLYLPP CYDDAAKPED VYKFEDLLSP AEYEALQSPS EAFRNVTSEE ILKMIEENSH CTFVIEALKS LPSDVESRDR QARCIWFLDT LIKFRAHRVV KRKSALGPGV PHIINTKLLK HFTCLTYNNG RLRNLISDSM KAKITAYVII LALHIHDFQI DLTVLQRDLK LSEKRMMEIA KAMRLKISKR KVSVAAGSEE DHKLGTLSLP LPPAQTSDRL AKRRKIT (104-419 aa encoded by BC014331 )
Target Information
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors (PubMed:24207024). Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (PubMed:24207024). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA-directed RNA polymerase I subunit E; DNA-directed RNA polymerase I subunit RPA49; FLJ13390; FLJ13970; polymerase (RNA) I associated factor 1; polymerase (RNA) I polypeptide E; polymerase (RNA) I polypeptide E, 53kDa; polymerase (RNA) I subunit E; RNA polymerase I associated factor (Paf53); RNA polymerase I subunit A49; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53; RP11-405L18.3
Gene Aliases: 53kDa; AU042259; D030019D19Rik; PAF53; POLR1E; PRAF1; RGD1565773
UniProt ID: (Human) Q9GZS1, (Mouse) Q8K202
Entrez Gene ID: (Human) 64425, (Mouse) 64424, (Rat) 313245
RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
rRNA transcription
positive regulation of gene expression, epigenetic
transcription, DNA-templated
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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