Immunogen sequence: VLHDEFIAH RLGLIPLISD DIVDKLQYSR DCTCEEFCPE CSVEFTLDVR CNEDQTRHVT SRDLISNSPR VIPVTSRNRD NDPNDYVEQD DILIVKLRKG QELRLRAYAK KGFGKEHAKW NPTAGVAFEY DPDNALRHTV YPKPEEWPKS EYSELDEDES QAPYDPNGKP ERFYYNVESC GSLRPETIVL SALSGLKKKL SDLQTQLSHE IQSDVLTIN (58-275 aa encoded by BC028157)
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft.
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Protein Aliases: DNA-directed RNA polymerase II 33 kDa polypeptide; DNA-directed RNA polymerase II subunit C; DNA-directed RNA polymerase II subunit RPB3; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; polymerase (RNA) II subunit C; polymerase II polypeptide C; RNA polymerase II 3; RNA polymerase II subunit 3; RNA polymerase II subunit B3; RPB31; RPB33
Gene Aliases: 33kDa; A-152E5.7; hRPB33; hsRPB3; mRBP31; POLR2C; RPB3; RPB31; Rpo2-3
Molecular Function: DNA-directed RNA polymerase