PA5-31255 targets POLR2C in WB applications and shows reactivity with Human samples.
The PA5-31255 immunogen is recombinant fragment corresponding to a region within amino acids 25 and 241 of Human POLR2C.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.
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Protein Aliases: DNA-directed RNA polymerase II 33 kDa polypeptide; DNA-directed RNA polymerase II subunit C; DNA-directed RNA polymerase II subunit RPB3; hRPB33; hsRPB3; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; polymerase (RNA) II subunit C; RNA polymerase II subunit 3; RNA polymerase II subunit B3; RPB3; RPB31; RPB33
Gene Aliases: A-152E5.7; hRPB33; hsRPB3; POLR2C; RPB3; RPB31
UniProt ID: (Human) P19387
Entrez Gene ID: (Human) 5432