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Invitrogen
POLR2D Polyclonal Antibody
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FIGURE: 1 / 2
POLR2D Antibody (PA5-102500) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded POLR2D in rat heart tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with POLR2D polyclonal antibody (Product # PA5-102500) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-102500
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human POLR2D(Accession O15514), corresponding to amino acid residues M1-S35.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total POLR2D.
Target Information
This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA-directed RNA polymerase II 16 kDa polypeptide; DNA-directed RNA polymerase II subunit D; DNA-directed RNA polymerase II subunit RPB4; plasma; polymerase (RNA) II (DNA directed) polypeptide D; polymerase (RNA) II subunit D; RNA polymerase II 16 kDa subunit; RNA polymerase II subunit B4; RNA polymerase II subunit hsRBP4; RPB16
Gene Aliases: 2310002G05Rik; 2610028L19Rik; HSRBP4; HSRPB4; POLR2D; RBP4; RPB16
UniProt ID: (Human) O15514, (Mouse) Q9D7M8
Entrez Gene ID: (Human) 5433, (Mouse) 69241, (Rat) 364834
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
mRNA splicing, via spliceosome
transcription-coupled nucleotide-excision repair
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
mRNA export from nucleus in response to heat stress
recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
somatic stem cell population maintenance
snRNA transcription from RNA polymerase II promoter
positive regulation of translational initiation
positive regulation of viral transcription
transcription, DNA-templated
cellular metabolic process
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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