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Product Details
PA5-139918
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human POLR2L. Recombinant protein control fragment (Product #RP-109363).
Conjugate
Form
Liquid
Concentration
0.2 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2926920
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: DALDALGLKR YCCRRMLLAH VDLIEKLLNY A
Target Information
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA-directed RNA polymerase III subunit L; DNA-directed RNA polymerases I, II, and III subunit RPABC5; hsRPB10b; polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa; polymerase (RNA) II subunit L; RNA polymerase II 7.6 kDa subunit; RNA polymerases I, II, and III subunit ABC5; RPB10 homolog; RPB7.6
Gene Aliases: hRPB7.6; POLR2L; RBP10; RPABC5; RPB10; RPB10beta; RPB7.6
UniProt ID: (Human) P62875
Entrez Gene ID: (Human) 5441
mRNA splicing, via spliceosome
transcription-coupled nucleotide-excision repair
regulation of transcription from RNA polymerase I promoter
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
transcription from RNA polymerase III promoter
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
positive regulation of type I interferon production
somatic stem cell population maintenance
snRNA transcription from RNA polymerase II promoter
positive regulation of gene expression, epigenetic
positive regulation of viral transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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