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Invitrogen
POLRMT Polyclonal Antibody
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Product Details
PA5-28196
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human mtRNA polymerase. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Amount
49 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA-directed RNA polymerase, mitochondrial; mitochondrial DNA-directed RNA polymerase; MtRPOL; polymerase (RNA) mitochondrial (DNA directed); unnamed protein product
Gene Aliases: 1110018N15Rik; 4932416K13; APOLMT; COXPD55; h-mtRPOL; MTRNAP; MTRPOL; POLRMT
UniProt ID: (Human) O00411, (Mouse) Q8BKF1
Entrez Gene ID: (Human) 5442, (Mouse) 216151
3'-5'-exoribonuclease activity
mitochondrial RNA polymerase regulatory region DNA binding
DNA binding
RNA binding
DNA-directed RNA polymerase activity
protein binding
transferase activity
nucleotidyltransferase activity
RNA polymerase activity
sequence-specific DNA binding
poly(A) RNA binding
DNA-directed RNA polymerase
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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