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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 420 and 697 of Human POMT1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29032 targets POMT1 in WB applications and shows reactivity with Human samples.
The PA5-29032 immunogen is recombinant fragment corresponding to a region within amino acids 420 and 697 of Human POMT1.
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dolichyl-phosphate-mannose--protein mannosyltransferase 1; LGMD2K; MDDGA1; MDDGB1; MDDGC1; protein O-mannosyl-transferase 1; protein-O-mannosyltransferase 1; RT; testis tissue sperm-binding protein Li 57p
LGMD2K; MDDGA1; MDDGB1; MDDGC1; POMT1; RT