MA5-17153 targets POU3F2 in pep-ELISA and WB applications and shows reactivity with Human samples.
The MA5-17153 immunogen is purified recombinant fragment of human POU3F2 (amino acids: 214-362) expressed in E. Coli.
MA5-17153 detects POU3F2 which has a predicted molecular weight of approximately 46.9kDa.
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
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Protein Aliases: 7-Oct; Brain-2; Brain-specific homeobox/POU domain protein 2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Oct-7; Octamer-binding protein 7; Octamer-binding transcription factor 7; OTF-7; POU domain, class 3, transcription factor 2
Gene Aliases: brn-2; BRN2; N-Oct3; oct-7; OCT7; OTF-7; OTF7; POU3F2; POUF3
UniProt ID: (Human) P20265
Entrez Gene ID: (Human) 5454