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POU4F3 Antibody (PA5-78116) in IHC (P)
POU4F3 Polyclonal Antibody detects POU4F3 protein at cytoplasm and nucleus in mouse eye by immunohistochemical analysis. Sample: Paraffin-embedded mouse eye. POU4F3 Polyclonal Antibody (Product # PA5-78116) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-78116
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human POU4F3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.11 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2736450
Product Specific Information
Positive Control: HeLa nuclear extract
Predicted Reactivity: Rat (98%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
POU4F3 encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain-3C; brain-specific homeobox POU domain protein 3C; Brain-specific homeobox/POU domain protein 3C; Brn-3.1; brn-3C; MGC138412; POU domain, class 4, transcription factor 3
Gene Aliases: Brn-3.1; Brn-3c; Brn3.1; BRN3C; ddl; DFNA15; dreidel; POU4F3
UniProt ID: (Human) Q15319, (Mouse) Q63955
Entrez Gene ID: (Human) 5459, (Mouse) 18998
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
DNA binding
sequence-specific DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
sensory perception of sound
vestibulocochlear nerve development
retinal ganglion cell axon guidance
inner ear morphogenesis
auditory receptor cell differentiation
positive regulation of transcription from RNA polymerase II promoter
axon extension
inner ear development
neuromuscular process controlling balance
neuron apoptotic process
inner ear receptor cell differentiation
visual perception
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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