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Product Details
PA5-77195
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human POU6F1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2720922
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain-5; Brain-specific homeobox/POU domain protein 5; brn-5; brn-5 protein; mPOU homeobox protein; octamer-binding transcription factor EMB; POU domain, class 6, transcription factor 1; transcription regulatory protein MCP-1
Gene Aliases: 2310038G18Rik; BRN5; C79593; cns-1; Emb; MPOU; POU6F1; TCFB1
UniProt ID: (Human) Q7Z7P6, (Rat) P56223
Entrez Gene ID: (Human) 5463, (Mouse) 19009, (Rat) 116545
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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