|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human POU6F2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: POU domain class 6 transcription factor 2; POU domain, class 6, transcription factor 2; POU6F2; Retina-derived POU domain factor 1; retina-derived POU-domain factor-1; RPF-1; RPF1; Wilms tumor suppressor locus
Gene Aliases: POU6F2; RPF-1; RPF1; WT5; WTSL
UniProt ID: (Human) P78424
Entrez Gene ID: (Human) 11281
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