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Invitrogen
PP2A beta Polyclonal Antibody
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Product Details
PA5-96230
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human PP2A Catalytic beta (NP_0010095521)
Conjugate
Form
Liquid
Concentration
0.70 mg/mL
Amount
70 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MDDKAFTKEL DQWVEQLNEC KQLNENQVRT LCEKAKEILT KESNVQEVRC PVTVCGDVHG QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER ITILRGNHES RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL SPSIDTLDHI RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH ANGLTLVSRA HQLVMEGYNW CHDRNVVTIF SAPNYCYRCG NQAAIMELDD TLKYSFLQFD PAPRRGEPHV TRRTPDYFL; Positive Samples: LO2, 293T, Mouse brain, Mouse lung, Mouse spleen, Rat liver; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, spindle pole
Target Information
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: phosphatase 2A; PP2A beta; PP2A-beta; PP2Abeta; PP2CB; PPP2bc; PPP2CB; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2A catalytic alpha subunit; protein phosphatase 2a, catalytic subunit, beta isoform; protein phosphatase type 2A catalytic subunit; protein phosphatase-2A-beta; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; testicular tissue protein Li 146; unnamed protein product
Gene Aliases: AI115466; D8Ertd766e; Pp2a2; PP2Abeta; PP2Ac; PP2CB; PPP2CB
UniProt ID: (Human) P62714, (Rat) P62716, (Mouse) P62715
Entrez Gene ID: (Human) 5516, (Rat) 24673, (Mouse) 19053
mitotic cell cycle
protein dephosphorylation
apoptotic mitochondrial changes
response to lead ion
regulation of gene expression
negative regulation of gene expression
negative regulation of tumor necrosis factor-mediated signaling pathway
regulation of microtubule polymerization
response to endoplasmic reticulum stress
response to hydrogen peroxide
negative regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of Ras protein signal transduction
response to antibiotic
regulation of neurofibrillary tangle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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